KEAP1 antibody (AA 422-449)

Catalog No. ABIN1539829

This Mouse Monoclonal antibody specifically detects KEAP1 in WB. It exhibits reactivity toward Human.

Quick Overview for KEAP1 antibody (AA 422-449) (ABIN1539829)

Target: KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KEAP1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 297CT6-1-6

Product Details anti-KEAP1 Antibody

Binding Specificity: AA 422-449

Predicted Reactivity: Pig

Purification: This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

Immunogen: This KEAP1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 422-449 amino acids from human KEAP1.

Isotype: IgM kappa

Application Details

Application Notes: WB: 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: KEAP1 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for KEAP1

Target: KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

Alternative Name: KEAP1

Background: This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

Molecular Weight: 69666

Gene ID: 9817

NCBI Accession: NP_036421, NP_987096

UniProt: Q14145

Pathways: Maintenance of Protein Location